Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03KTE
|
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| Former ID |
DIB001313
|
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| Drug Name |
LGD2941
|
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| Drug Type |
Small molecular drug
|
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| Indication | Osteoporosis [ICD9: 733.0, V07.4; ICD10:M80-M81, Z79.890] | Discontinued in Phase 1 | [547162] | ||
| Company |
Ligand Pharmaceuticals
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C17H16F6N2O2
|
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| Canonical SMILES |
CC1CCC(N1C2=CC3=C(C=C2)NC(=O)C=C3C(F)(F)F)C(C(F)(F)F)O
|
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| InChI |
1S/C17H16F6N2O2/c1-8-2-5-13(15(27)17(21,22)23)25(8)9-3-4-12-10(6-9)11(16(18,19)20)7-14(26)24-12/h3-4,6-8,13,15,27H,2,5H2,1H3,(H,24,26)/t8-,13-,15-/m1/s1
|
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| InChIKey |
HWLLYFXDDGGHOE-BCSUUIJWSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Androgen receptor | Target Info | Modulator | [530124] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Coregulation of Androgen receptor activity | |||||
| Regulation of Androgen receptor activity | |||||
| Nongenotropic Androgen signaling | |||||
| Regulation of nuclear beta catenin signaling and target gene transcription | |||||
| FOXA1 transcription factor network | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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