Drug General Information
Drug ID
D0A9MR
Former ID
DAP001208
Drug Name
Norgestrel
Synonyms
Capronor; DNorgestrel; Follistrel; Jadelle; Levlen; Levonelle; Levonorgestrel; Levonorgestrelum; Levonova; Methylnorethindrone; Microgyn; Microlut; Microlution; Microluton; Microval; Mirena; Monovar; NORPLANT; Neogest; NorLevo; Nordet; Norgeston; Norgestrelum; Ovranette; Ovrette; Postinor; Preven; Tetragynon; Triagynon; Triciclor; Trigoa; Trivora; LD norgestrel [French]; Ld norgestrel; Levlen ED; Levonorgestrel implants; Logynon ED; Microgest ED; Microgynon CD; Norgestrel [Progestins]; Norplant II; Norplant System in Plastic Container; Plan B; Triquilar ED; Microgynon 21; Microgynon 28; Microgynon 30 ED; Minivlar 30; Monofeme 28; Neogynon 21; Nordette 21; Nordette 28; Norplant 2; SH 70850; SH 850; Stediril 30; Trifeme 28; Trinordiol 21; Trinordiol 28; Triphasil 21; Triphasil 28; Wy 3707; Alpha-Norgestrel; Component of Lo/ovral; D-Norgestrel; Dl-Norgestrel; FH 122-A; LO/Ovral; Levonorgestrelum [INN-Latin]; Levora-21; Levora-28; Mirena (TN); Norgestrelum [INN-Latin]; Norplant (TN); Norplant-2; Ovoplex 30-150; Ovral-Lo; Ovrette (TN); Postinor-2; Rigevidon 21+7; SOH-075; Tri-Levlen 21; Wy-3707; Wy-5104; E-Gen-C; Levonorgestrel [USAN:INN:BAN]; D(-)-Norgestrel; Levonorgestrel (JAN/USP/INN); Norgestrel (JP15/USP/INN); Norgestrel [USAN:BAN:INN:JAN]; Norgestrel [USAN:INN:BAN:JAN]; D-(-)-Norgestrel; Levonelle, D-Norgestrel, Levonova, Levonorgestrel; Norgestrel-(-)-D; Dl-13-beta-Ethyl-17-alpha-ethynyl-19-nortestosterone; (-)-Norgestrel; 13-BETA-ETHYL-17-ALPHA-ETHYNYL-17-BETA-HYDROXYGON-4-EN-3-ONE; 13-Ehyl-17alpha-ethynyl-17-hydroxygon-4-en-3-one; 13-Ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one; 13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one; 13-Ethyl-17alpha-ethynylgon-4-en-17beta-ol-3-one; 13-beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one; 13beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one; 17-Ethynyl-18-methyl-19-nortestosterone; 17-alpha-Ethynyl-13-ethyl-19-nortestosterone; 17alpha-Ethynyl-13-ethyl-19-nortestosterone; 17alpha-Ethynyl-13beta-ethyl-3-oxo-4-estren-17beta-ol; 17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one; 17alpha-Ethynyl-18-homo-19-nor-testosterone; 17alpha-Ethynyl-18-homo-19-nortestosterone; 17alpha-ethynyl-17beta-hydroxy-18a-homoestr-4-en-3-one; 18,19-Dinor-4-pregnen-20-yn-3-one; 18-Methyl-17-alpha-ethynyl-19-nortestosterone; 18-Methylnorethisterone; 72-HOURS
Drug Type
Small molecular drug
Indication Contraception [ICD10:Z30] Approved [538483], [551871]
Therapeutic Class
Contraceptive Agents
Structure
Download
2D MOL

3D MOL

Formula
C21H28O2
Canonical SMILES
CCC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
InChI
1S/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1
InChIKey
WWYNJERNGUHSAO-XUDSTZEESA-N
CAS Number
CAS 6533-00-2
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:7630
SuperDrug ATC ID
G03AC03; G03AD01
SuperDrug CAS ID
cas=000797637
Target and Pathway
Target(s) Progesterone receptor Target Info Agonist [536668]
KEGG Pathway Oocyte meiosis
Progesterone-mediated oocyte maturation
Pathway Interaction Database Cellular roles of Anthrax toxin
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathway
WikiPathways Ovarian Infertility Genes
Signaling by ERBB4
Nuclear Receptors
References
Ref 538483FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 017031.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536668Toll-like receptor-4-mediated macrophage activation is differentially regulated by progesterone via the glucocorticoid and progesterone receptors. Immunology. 2008 Sep;125(1):59-69. Epub 2008 Mar 28.

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