Drug Information

Drug General Information
Drug ID
D0UL2L
Former ID
DIB015995
Drug Name
Lornoxicam
Synonyms
CTX; Chlortenoxicam; Lorcam; Safem; Telos; Xefo; Xefo Rapid; HN-10000; TS-110; Ro-13-9297
Drug Type
Small molecular drug
Indication Migraine [ICD9: 346; ICD10:G43] Approved [522825], [551871]
Company
Roche Holding AG
Structure
Download
2D MOL

3D MOL
Formula
C13H10ClN3O4S2
Canonical SMILES
S1(=O)(=O)c2c(C(=C(N1C)C(=O)Nc1ncccc1)O)sc(c2)Cl
CAS Number
CAS 70374-39-9
PubChem Compound ID
54690031
Target and Pathway
Target(s) Cyclooxygenase Target Info Modulator [525560], [551871]
References
Ref 522825ClinicalTrials.gov (NCT00997750) Efficacy and Safety of Lornoxicam in Patients With Acute Coronary Syndrome. U.S. National Institutes of Health.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 525560The analgesic NSAID lornoxicam inhibits cyclooxygenase (COX)-1/-2, inducible nitric oxide synthase (iNOS), and the formation of interleukin (IL)-6 in vitro. Inflamm Res. 1999 Jul;48(7):369-79.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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