Drug General Information
Drug ID
D06ALD
Former ID
DNCL002850
Drug Name
Empagliflozin
Drug Type
Small molecular drug
Indication Type 1 diabetes [ICD9: 250; ICD10:E10] Approved [467995], [533123]
Company
Boehringer Ingelheim Pharmaceuticals; Eli Lilly
Structure
Download
2D MOL

3D MOL

Formula
C23H27ClO7
InChI
InChI=1S/C23H27ClO7/c24-18-6-3-14(23-22(28)21(27)20(26)19(11-25)31-23)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21-,22+,23-/m0/s1
InChIKey
OBWASQILIWPZMG-QZMOQZSNSA-N
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
A10BX12
Target and Pathway
Target(s) SLGT2 Target Info Modulator [533123]
Reactome Hexose transport
Na+-dependent glucose transporters
Inositol transporters
WikiPathways NRF2 pathway
Nuclear Receptors Meta-Pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 467995(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4754).
Ref 5331232014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81.
Ref 5331232014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81.

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