Drug Information
Drug General Information | |||||
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Drug ID |
D07BVI
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Former ID |
DAP001561
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Drug Name |
Ipilimumab
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Synonyms |
BMS-734016; MDX-010; MDX-101; Yervoy (TN)
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Drug Type |
Antibody
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Company |
Bristol-Myers Squibb
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CAS Number |
CAS 477202-00-9
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SuperDrug ATC ID |
L01XC11
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Target and Pathway | |||||
Target(s) | Cytotoxic T-lymphocyte protein 4 | Target Info | [531351] | ||
Pathway Interaction Database | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | ||||
Reactome | CTLA4 inhibitory signaling | ||||
References | |||||
Ref 531351 | Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5. | ||||
Ref 531783 | 2011 FDA drug approvals. Nat Rev Drug Discov. 2012 Feb 1;11(2):91-4. | ||||
Ref 541945 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6888). |
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