Drug Information

Drug General Information
Drug ID
D0S9CI
Former ID
DIB020465
Drug Name
N',2-diphenylquinoline-4-carbohydrazide 8m
Synonyms
compound 8m [PMID:16950617]
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528419]
Structure
Download
2D MOL
Formula
C33H36FN5O3
InChI
InChI=1S/C33H36FN5O3/c1-33(2,3)38-20-18-37(19-21-38)22-26-28(31(40)36-39(32(41)42-4)24-14-9-6-10-15-24)25-16-11-17-27(34)30(25)35-29(26)23-12-7-5-8-13-23/h5-17H,18-22H2,1-4H3,(H,36,40)
InChIKey
KQNYTTDHCMFOME-UHFFFAOYSA-N
PubChem Compound ID
11989776
PubChem Substance ID
17488845, 24496149, 37438155, 79125715, 103505669, 104076837, 135650673, 248134922
Target and Pathway
Target(s) Nigral tachykinin NK(3) receptor Target Info Antagonist [528419]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 528419N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5752-6. Epub 2006 Sep 6.
Ref 528419N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5752-6. Epub 2006 Sep 6.

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