Drug Information
Drug General Information | |||||
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Drug ID |
D00BMI
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Former ID |
DNC009401
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Drug Name |
N-1,3,4-thiadiazol-2-ylsulfamide
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [529794] | ||
Structure |
Download2D MOL |
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Formula |
C2H4N4O2S2
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Canonical SMILES |
C1=NN=C(S1)NS(=O)(=O)N
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InChI |
1S/C2H4N4O2S2/c3-10(7,8)6-2-5-4-1-9-2/h1H,(H,5,6)(H2,3,7,8)
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InChIKey |
TXIIDPYBTNXTDC-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Carbonic anhydrase IV | Target Info | Inhibitor | [529794] | |
Carbonic anhydrase I | Target Info | Inhibitor | [529794] | ||
Carbonic anhydrase II | Target Info | Inhibitor | [529794] | ||
NetPath Pathway | IL4 Signaling Pathway | ||||
EGFR1 Signaling Pathway | |||||
Pathway Interaction Database | C-MYB transcription factor network | ||||
PathWhiz Pathway | Gastric Acid Production | ||||
References | |||||
Ref 529794 | Bioorg Med Chem Lett. 2008 Dec 15;18(24):6332-5. Epub 2008 Nov 1.Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV. | ||||
Ref 529794 | Bioorg Med Chem Lett. 2008 Dec 15;18(24):6332-5. Epub 2008 Nov 1.Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV. |
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