Drug General Information
Drug ID	D08YYX
Former ID	DNC012629
Drug Name	6-(2-Amino-ethyl)-biphenyl-2,3-diol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533481]
Structure		Download 2D MOL 3D MOL
Formula	C14H15NO2
Canonical SMILES	C1=CC=C(C=C1)C2=C(C=CC(=C2O)O)CCN
InChI	1S/C14H15NO2/c15-9-8-11-6-7-12(16)14(17)13(11)10-4-2-1-3-5-10/h1-7,16-17H,8-9,15H2
InChIKey	DAKLNHHLHPIOPS-UHFFFAOYSA-N
PubChem Compound ID	13678304
Target and Pathway
Target(s)	Dopamine D1 receptor	Target Info	Inhibitor	[533481]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Morphine addiction
	Alcoholism
PANTHER Pathway	Dopamine receptor mediated signaling pathway
PathWhiz Pathway	Dopamine Activation of Neurological Reward System
Reactome	Dopamine receptors
	G alpha (s) signalling events
WikiPathways	Hypothetical Network for Drug Addiction
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Genes and (Common) Pathways Underlying Drug Addiction
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 533481	J Med Chem. 1986 Oct;29(10):1904-12.Synthesis and dopaminergic binding of 2-aryldopamine analogues: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes.
Ref 533481	J Med Chem. 1986 Oct;29(10):1904-12.Synthesis and dopaminergic binding of 2-aryldopamine analogues: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes.

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