Drug General Information
Drug ID
D0W0MF
Former ID
DAP000670
Drug Name
Talbutal
Synonyms
Lotusate; Profundol; Talbumalum; Talbutale; Talbutalum; Talbutal [INN]; Talbutale [DCIT]; WIN 5095; Lotusate (TN); Sec-Butyl allylbarbituric acid; Talbutal (INN); Talbutalum [INN-Latin]; 5-(1-Methylpropyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-(1-methylpropyl)-5-prop-2-en-1-ylpyrimidine-2,4,6(1H,3H,5H)-trione; 5-Allyl-5-(1-methylpropyl) barbituric acid; 5-Allyl-5-sec-butylbarbituric acid; 5-Isobutyl-5-allylbarbituric acid; 5-butan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
Drug Type
Small molecular drug
Indication Sedation [ICD9: 338; ICD10:R52, G89] Approved [538418]
Therapeutic Class
Hypnotics and Sedatives
Structure
Download
2D MOL

3D MOL

Formula
C11H16N2O3
Canonical SMILES
CCC(C)C1(C(=O)NC(=O)NC1=O)CC=C
InChI
1S/C11H16N2O3/c1-4-6-11(7(3)5-2)8(14)12-10(16)13-9(11)15/h4,7H,1,5-6H2,2-3H3,(H2,12,13,14,15,16)
InChIKey
BJVVMKUXKQHWJK-UHFFFAOYSA-N
CAS Number
CAS 115-44-6
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
N05CA07
SuperDrug CAS ID
cas=000115446
Target and Pathway
Target(s) GABA A receptor Target Info Modulator [556264]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 538418FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 009410.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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