Drug Information
Drug General Information | |||||
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Drug ID |
D0A6BH
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Former ID |
DNC003050
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Drug Name |
5,10-Methylene-6-Hydrofolic Acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [551393] | ||
Structure |
Download2D MOL |
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Formula |
C20H21N7O6
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Canonical SMILES |
C1C2C=NC3=C(N2CN1C4=CC=C(C=C4)C(=O)NC(CCC(=O)O)C(=O)O)C<br />(=O)N=C(N3)N
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InChI |
1S/C20H21N7O6/c21-20-24-16-15(18(31)25-20)27-9-26(8-12(27)7-22-16)11-3-1-10(2-4-11)17(30)23-13(19(32)33)5-6-14(28)29/h1-4,7,12-13H,5-6,8-9H2,(H,23,30)(H,28,29)(H,32,33)(H3,21,24,25,31)/t12-,13-/m1/s1
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InChIKey |
BHJAPJNOACHPNI-CHWSQXEVSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Thymidylate synthase | Target Info | Inhibitor | [551393] | |
BioCyc Pathway | Pyrimidine deoxyribonucleotides biosynthesis from CTP | ||||
Pyrimidine deoxyribonucleotides de novo biosynthesis | |||||
Superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis | |||||
Superpathway of pyrimidine deoxyribonucleoside salvage | |||||
DTMP de novo biosynthesis (mitochondrial) | |||||
Pyrimidine deoxyribonucleosides salvage | |||||
Pathway Interaction Database | E2F transcription factor network | ||||
PathWhiz Pathway | Pyrimidine Metabolism | ||||
WikiPathways | Trans-sulfuration and one carbon metabolism | ||||
Retinoblastoma (RB) in Cancer | |||||
One Carbon Metabolism | |||||
Integrated Pancreatic Cancer Pathway | |||||
miR-targeted genes in muscle cell - TarBase | |||||
miR-targeted genes in lymphocytes - TarBase | |||||
miR-targeted genes in leukocytes - TarBase | |||||
miR-targeted genes in epithelium - TarBase | |||||
Metabolism of nucleotides | |||||
Fluoropyrimidine Activity | |||||
References |
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