Drug Information

Drug General Information
Drug ID
D0P9BM
Former ID
DIB018593
Drug Name
3-hydroxybenzylhydrazine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [468180]
Structure
Download
2D MOL
Formula
C7H10N2O
InChI
InChI=1S/C7H10N2O/c8-9-5-6-2-1-3-7(10)4-6/h1-4,9-10H,5,8H2
InChIKey
OFKWWALNMPEOSZ-UHFFFAOYSA-N
PubChem Compound ID
1663
PubChem Substance ID
4360729, 8151225, 11111287, 11342056, 11362239, 11363207, 11365769, 11368331, 11371572, 11374756, 11376493, 11487641, 11490542, 11493023, 11494127, 15321454, 29220867, 47213191, 47662405, 47885515, 48259354, 49977856, 50111091, 57320971, 79416695, 85789594, 99381461, 103124619, 103412798, 103979614, 104298359, 117532451, 117616384, 124749843, 124880362, 125000147, 125651768, 128801323, 134978313, 137051850, 139981395, 152090465, 162888077, 163590322, 178101809, 179039718, 198971316, 223581674, 226523846, 249550046
Target and Pathway
Target(s) Aromatic-L-amino-acid decarboxylase Target Info Inhibitor [543396]
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation via tryptamine
Serotonin and melatonin biosynthesis
Catecholamine biosynthesis
KEGG Pathway Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Metabolic pathways
Serotonergic synapse
Dopaminergic synapse
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
5-Hydroxytryptamine biosynthesis
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
PathWhiz Pathway Catecholamine Biosynthesis
Tyrosine Metabolism
Tryptophan Metabolism
WikiPathways SIDS Susceptibility Pathways
Biogenic Amine Synthesis
Tryptophan metabolism
Dopaminergic Neurogenesis
Metabolism of amino acids and derivatives
Dopamine metabolism
Parkinsons Disease Pathway
Nicotine Activity on Dopaminergic Neurons
References
Ref 468180(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5116).
Ref 543396(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1271).

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