Drug Information

Drug General Information
Drug ID
D0T5VG
Former ID
DNC009686
Drug Name
2-(Aminomethyl)-5-(1'-naphthethyl)tetrahydrofuran
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529955]
Structure
Download
2D MOL

3D MOL
Formula
C17H21NO
Canonical SMILES
C1CC(OC1CCC2=CC=CC3=CC=CC=C32)CN
InChI
1S/C17H21NO/c18-12-16-11-10-15(19-16)9-8-14-6-3-5-13-4-1-2-7-17(13)14/h1-7,15-16H,8-12,18H2
InChIKey
QLXIMJBRAWACSR-UHFFFAOYSA-N
PubChem Compound ID
11514389
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Inhibitor [529955]
Sodium-dependent serotonin transporter Target Info Inhibitor [529955]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 529955Bioorg Med Chem. 2009 Mar 1;17(5):2047-68. Epub 2009 Jan 15.2,5-Disubstituted tetrahydrofurans as selective serotonin re-uptake inhibitors.
Ref 529955Bioorg Med Chem. 2009 Mar 1;17(5):2047-68. Epub 2009 Jan 15.2,5-Disubstituted tetrahydrofurans as selective serotonin re-uptake inhibitors.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.