Drug General Information
Drug ID	D0B8SE
Former ID	DIB019108
Drug Name	CGP 46381
Synonyms	CGP-46381; CGP46381
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538667]
Structure		Download 2D MOL
Formula	C10H22NO2P
InChI	InChI=1S/C10H22NO2P/c11-7-4-8-14(12,13)9-10-5-2-1-3-6-10/h10H,1-9,11H2,(H,12,13)
InChIKey	XOESDNIUAWGCLU-UHFFFAOYSA-N
PubChem Compound ID	130022
PubChem Substance ID	6523733, 7978466, 10242503, 11113994, 14797909, 26752135, 29308716, 47731190, 48179669, 48253903, 48404433, 50421181, 57343248, 85230053, 91746557, 92729729, 103336381, 104371816, 126436780, 129717070, 135085418, 135650070, 142796837, 179236190, 224185686, 226727334, 241182269, 241375320
Target and Pathway
Target(s)	GABAB receptor	Target Info	Antagonist	[525914]
References
Ref 538667	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1086).
Ref 525914	The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen. Br J Pharmacol. 2000 Nov;131(6):1050-4.

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