TTD | Drug: D0B3PC

Drug General Information
Drug ID	D0B3PC
Former ID	DIB021107
Drug Name	UCB35625
Synonyms	UCB 35625; UCB-35625
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540468]
Structure		Download 2D MOL
Formula	C28H35Cl2N2O2+
InChI	InChI=1S/C28H34Cl2N2O2/c1-32(18-19-6-4-2-3-5-7-19)14-12-22(13-15-32)31-28(33)27-23-16-20(29)8-10-25(23)34-26-11-9-21(30)17-24(26)27/h8-11,16-17,19,22,27H,2-7,12-15,18H2,1H3/p+1
InChIKey	AHYGVFSLUXGXSH-UHFFFAOYSA-O
PubChem Compound ID	458342
PubChem Substance ID	607763, 7979263, 50905218, 57405491, 109723867, 178100515, 246412766
Target and Pathway
Target(s)	CC chemokine receptor	Target Info	Antagonist	[525795]
KEGG Pathway	Cytokine-cytokine receptor interaction
KEGG Pathway	Chemokine signaling pathway
Reactome	Beta defensins
	Binding and entry of HIV virion
	Chemokine receptors bind chemokines
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 540468	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3536).
Ref 525795	A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry. J Biol Chem. 2000 Aug 25;275(34):25985-92.

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Drug Information