Drug General Information
Drug ID	D0V1DW
Former ID	DNC009162
Drug Name	3,4,5-tribromo-2-(2', 4'-dibromo-phenoxy)phenol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551365]
Structure		Download 2D MOL 3D MOL
Formula	C12H5Br5O2
Canonical SMILES	C1=CC(=C(C=C1Br)Br)OC2=C(C(=C(C=C2O)Br)Br)Br
InChI	1S/C12H5Br5O2/c13-5-1-2-9(6(14)3-5)19-12-8(18)4-7(15)10(16)11(12)17/h1-4,18H
InChIKey	LNZHBUPVHNJGJG-UHFFFAOYSA-N
PubChem Compound ID	11952901
Target and Pathway
Target(s)	GMP synthase [glutamine-hydrolyzing]	Target Info	Inhibitor	[551365]
BioCyc Pathway	Guanosine nucleotides de novo biosynthesis
	Superpathway of purine nucleotide salvage
	Purine nucleotides de novo biosynthesis
	Guanosine ribonucleotides de novo biosynthesis
KEGG Pathway	Purine metabolism
	Drug metabolism - other enzymes
	Metabolic pathways
PANTHER Pathway	De novo purine biosynthesis
PathWhiz Pathway	Glutamate Metabolism
	Purine Metabolism
Reactome	Purine ribonucleoside monophosphate biosynthesis
WikiPathways	Metabolism of nucleotides
References
Ref 551365	Enzyme inhibitors: new and known polybrominated phenols and diphenyl ethers from four Indo-Pacific Dysidea sponges. J Nat Prod. 1995 Sep;58(9):1384-91.
Ref 551365	Enzyme inhibitors: new and known polybrominated phenols and diphenyl ethers from four Indo-Pacific Dysidea sponges. J Nat Prod. 1995 Sep;58(9):1384-91.

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