Drug Information
Drug General Information | |||||
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Drug ID |
D08ZBV
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Former ID |
DNC003719
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Drug Name |
L-732138
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Terminated | [546118] | ||
Structure |
Download2D MOL |
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Formula |
C22H18F6N2O3
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Canonical SMILES |
CC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)OCC3=CC(=CC(=C3)C(F)(F<br />)F)C(F)(F)F
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InChI |
1S/C22H18F6N2O3/c1-12(31)30-19(8-14-10-29-18-5-3-2-4-17(14)18)20(32)33-11-13-6-15(21(23,24)25)9-16(7-13)22(26,27)28/h2-7,9-10,19,29H,8,11H2,1H3,(H,30,31)/t19-/m0/s1
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InChIKey |
BYYQYXVAWXAYQC-IBGZPJMESA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Substance-P receptor | Target Info | Inhibitor | [530392] | |
NK-2 receptor | Target Info | Inhibitor | [531023] | ||
PANTHER Pathway | CCKR signaling map ST | ||||
References | |||||
Ref 530392 | Bioorg Med Chem. 2009 Oct 15;17(20):7337-43. Epub 2009 Aug 21.The biological activity and metabolic stability of peptidic bifunctional compounds that are opioid receptor agonists and neurokinin-1 receptor antagonists with a cystine moiety. | ||||
Ref 531023 | J Med Chem. 2010 Aug 12;53(15):5491-501.Biological and conformational evaluation of bifunctional compounds for opioid receptor agonists and neurokinin 1 receptor antagonists possessing two penicillamines. |
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