Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07NXB
|
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| Former ID |
DNC003515
|
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| Drug Name |
Ro-151310
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [534008] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C15H14ClN3O3
|
||||
| Canonical SMILES |
CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)Cl)C
|
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| InChI |
1S/C15H14ClN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
|
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| InChIKey |
QORLMYYHZLDYOR-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Gamma-aminobutyric-acid receptor alpha-2 subunit | Target Info | Inhibitor | [531044] | |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Target Info | Inhibitor | [534008] | ||
| Gamma-aminobutyric-acid receptor alpha-3 subunit | Target Info | Inhibitor | [531044] | ||
| Gamma-aminobutyric acid receptor | Target Info | Inhibitor | [531044] | ||
| Gamma-aminobutyric-acid receptor alpha-5 subunit | Target Info | Inhibitor | [531044] | ||
| Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Inhibitor | [534008] | ||
| Gamma-aminobutyric acid receptor subunit beta-2 | Target Info | Inhibitor | [534008] | ||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
| Iron uptake and transportWP706:SIDS Susceptibility Pathways | |||||
| Iron uptake and transport | |||||
| References | |||||
| Ref 531044 | Bioorg Med Chem. 2010 Nov 15;18(22):7731-8. Epub 2010 Jun 1.The GABA(A) receptor as a target for photochromic molecules. | ||||
| Ref 534008 | J Med Chem. 1993 Apr 16;36(8):1001-6.Synthesis and evaluation of imidazo[1,5-a][1,4]benzodiazepine esters with high affinities and selectivities at "diazepam-insensitive" benzodiazepine receptors. | ||||
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