Drug Information

Drug General Information
Drug ID
D0K6GZ
Former ID
DAP000161
Drug Name
Sparfloxacin
Synonyms
Esparfloxacino; SPFX; Spara; Sparfloxacine; Sparfloxacinum; Zagam; AT 4140; CP 103826; PD 131501; PD131501; AT-4140; CP-103826; DRG-0143; Esparfloxacino [INN-Spanish]; Liposome-encapsulated sparfloxacin; PD 1315-1; PD-131501; RP-64206; Respipac (TN); Sparfloxacin & RU 40555; Sparfloxacine [INN-French]; Sparfloxacinum [INN-Latin]; Zagam (TN); Sparfloxacin, cis-isomer; Sparfloxacin (JAN/USAN/INN); Sparfloxacin [USAN:BAN:INN:JAN]; Cis-5-Amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; (cis)-5-amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 5-Amino-1-cyclohexyl-7-(cis-3,5-dimethylpiperazino)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 5-Amino-1-cyclopropyl-7-(cis-3,5-dimethyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid & RU 40555; 5-Amino-1-cyclopropyl-7-(cis-3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxoquinoline-3-carboxylic acid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [538553]
Therapeutic Class
Antibiotics
Company
Square pharma
Structure
Download
2D MOL

3D MOL
Formula
C19H22F2N4O3
Canonical SMILES
CC1CN(CC(N1)C)C2=C(C3=C(C(=C2F)N)C(=O)C(=CN3C4CC4)C(=O)<br />O)F
InChI
1S/C19H22F2N4O3/c1-8-5-24(6-9(2)23-8)17-13(20)15(22)12-16(14(17)21)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6,22H2,1-2H3,(H,27,28)/t8-,9+
InChIKey
DZZWHBIBMUVIIW-DTORHVGOSA-N
CAS Number
CAS 110871-86-8
PubChem Compound ID
60464
PubChem Substance ID
9864, 602967, 603315, 627689, 7847656, 7980640, 8147220, 8186880, 11528734, 12014309, 14830034, 16618671, 24860661, 24880518, 25623210, 26719819, 29218052, 43117868, 46386584, 46506453, 48416549, 56313707, 57314019, 57648946, 57651613, 78600880, 85279509, 92309275, 92710927, 103223807, 104225171, 104320846, 117393504, 124766044, 124893258, 125325629, 126631379, 126682799, 127811456, 131294555, 131905130, 134223183, 134337481, 135018692, 137003456, 142971059, 144205133, 160845924, 160964541, 163414061
ChEBI ID
ChEBI:9212
SuperDrug ATC ID
J01MA09
SuperDrug CAS ID
cas=110871868
Target and Pathway
Target(s) Bacterial DNA gyrase Target Info Modulator [556264]
Topoisomerase IV Target Info Modulator [556264]
References
Ref 538553FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020677.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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