Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0X2MQ
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| Former ID |
DIB018493
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| Drug Name |
17-phenyl-omega-trinor-PGE2
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| Synonyms |
17-phenyl-omega-trinor-prostaglandin E2; 17-phenyl-trinor-PGE2; 17-Ph-omega-trinor-PGE2; 17-phenyl-PGE2
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [539213] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C23H30O5
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| InChI |
InChI=1S/C23H30O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,14-15,18-20,22,24,26H,2,7,10-13,16H2,(H,27,28)/b6-1-,15-14+/t18-,19+,20+,22+/m0/s1
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| InChIKey |
FOBVMYJQWZOGGJ-XYRJXBATSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
4266001, 7978573, 11038725, 15474352, 26754834, 26754835, 39316485, 47440000, 47736222, 50110796, 57358833, 74660904, 85787435, 92309785, 99300699, 99302217, 104046454, 113859000, 131342668, 135651383, 137146293, 142622838, 143020475, 179150412, 186016875, 229390806, 242475231, 250134045, 252377742, 252455509, 252457339, 252464504
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| Target and Pathway | |||||
| Target(s) | Prostaglandin E2 receptor, EP1 subtype | Target Info | Agonist | [534595] | |
| Prostaglandin E2receptor, EP2 subtype | Target Info | Agonist | [534595] | ||
| Prostaglandin E2 receptor EP3 subtype | Target Info | Agonist | [534478] | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Pathways in cancerhsa04024:cAMP signaling pathway | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| Renin secretion | |||||
| Pathways in cancerhsa04020:Calcium signaling pathway | |||||
| cAMP signaling pathway | |||||
| Regulation of lipolysis in adipocytes | |||||
| Pathways in cancer | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | PI3 kinase pathway | ||||
| References | |||||
| Ref 534478 | Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24. | ||||
| Ref 534595 | Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. Eur J Pharmacol. 1997 Dec 11;340(2-3):227-41. | ||||
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