Drug Information

Drug General Information
Drug ID
D0V9XF
Former ID
DNC014803
Drug Name
PICROTIN
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467624]
Structure
Download
2D MOL

3D MOL
Formula
C15H18O7
InChI
InChI=1S/C15H18O7/c1-12(2,18)6-7-10(16)20-8(6)9-13(3)14(7,19)4-5-15(13,22-5)11(17)21-9/h5-9,18-19H,4H2,1-3H3/t5-,6+,7-,8-,9-,13-,14-,15+/m1/s1
InChIKey
RYEFFICCPKWYML-QCGISDTRSA-N
PubChem Compound ID
442291
PubChem Substance ID
11719, 8149144, 10298999, 11335931, 11361170, 11363307, 11365869, 11368431, 11371205, 11375459, 11376593, 11462142, 11483894, 11488095, 11489889, 11493595, 11494227, 11537361, 12174785, 14800915, 26611500, 26680147, 29204484, 36885859, 47440284, 47440285, 48259258, 48259259, 48484021, 50109819, 50956284, 57403989, 87352014, 92124834, 99301844, 103639231, 104115363, 104627248, 124558826, 124637665, 134352008, 135118322, 137241488, 141839280, 144204357, 144204813, 178101103, 179039605, 198977117, 198983475
Target and Pathway
Target(s) Glycine receptor Target Info Inhibitor [528770]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Ligand-gated ion channel transport
WikiPathways Iron uptake and transport
References
Ref 467624(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4286).
Ref 528770J Biol Chem. 2007 Jun 1;282(22):16016-35. Epub 2007 Apr 3.Mechanisms for picrotoxinin and picrotin blocks of alpha2 homomeric glycine receptors.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.