Drug Information

Drug General Information
Drug ID
D01OXV
Former ID
DIB019923
Drug Name
GNE-9605
Synonyms
GNE 9605; GNE9605
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532594]
Structure
Download
2D MOL
Formula
C17H20ClF4N7O
InChI
InChI=1S/C17H20ClF4N7O/c1-23-15-10(17(20,21)22)4-24-16(27-15)26-12-5-25-29(14(12)18)13-2-3-28(6-11(13)19)9-7-30-8-9/h4-5,9,11,13H,2-3,6-8H2,1H3,(H2,23,24,26,27)/t11-,13-/m0/s1
InChIKey
PUXPEQJKNAWNQA-AAEUAGOBSA-N
PubChem Compound ID
76328936
PubChem Substance ID
194174690, 194946006, 207761501, 210274778, 210280411, 223218470, 249565602, 249714985, 251961377
Target and Pathway
Target(s) leucine-rich repeat kinase 2 Target Info Inhibitor [532594]
References
Ref 532594Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. J Med Chem. 2014 Feb 13;57(3):921-36.
Ref 532594Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. J Med Chem. 2014 Feb 13;57(3):921-36.

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