Drug Information
Drug General Information | |||||
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Drug ID |
D02AYI
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Former ID |
DNC009583
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Drug Name |
2-(4-phenoxyphenoxy)ethanamine
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [529868] | ||
Structure |
Download2D MOL |
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Formula |
C14H15NO2
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Canonical SMILES |
C1=CC=C(C=C1)OC2=CC=C(C=C2)OCCN
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InChI |
1S/C14H15NO2/c15-10-11-16-12-6-8-14(9-7-12)17-13-4-2-1-3-5-13/h1-9H,10-11,15H2
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InChIKey |
FBLANPWAVFBRNS-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Phospholipase A2, membrane associated | Target Info | Inhibitor | [529868] | |
Leukotriene A-4 hydrolase | Target Info | Inhibitor | [529770] | ||
BioCyc Pathway | PhospholipasesPWY66-375:Leukotriene biosynthesis | ||||
KEGG Pathway | Glycerophospholipid metabolism | ||||
Ether lipid metabolism | |||||
Arachidonic acid metabolism | |||||
Linoleic acid metabolism | |||||
alpha-Linolenic acid metabolism | |||||
Metabolic pathways | |||||
Ras signaling pathway | |||||
Vascular smooth muscle contraction | |||||
Pancreatic secretion | |||||
Fat digestion and absorptionhsa00590:Arachidonic acid metabolism | |||||
Pathway Interaction Database | Glypican 1 network | ||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
References | |||||
Ref 529770 | Bioorg Med Chem Lett. 2008 Dec 15;18(24):6549-52. Epub 2008 Oct 14.Activation and inhibition of leukotriene A4 hydrolase aminopeptidase activity by diphenyl ether and derivatives. | ||||
Ref 529868 | J Med Chem. 2008 Dec 25;51(24):7882-8.Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching. |
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