Drug Information

Drug General Information
Drug ID
D04QBM
Former ID
DIB020181
Drug Name
L-803,087
Synonyms
L803087
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539318]
Structure
Download
2D MOL
Formula
C25H29F2N5O3
InChI
InChI=1S/C25H29F2N5O3/c1-35-24(34)20(10-6-12-30-25(28)29)31-21(33)11-5-9-17-18-13-16(26)14-19(27)23(18)32-22(17)15-7-3-2-4-8-15/h2-4,7-8,13-14,20,32H,5-6,9-12H2,1H3,(H,31,33)(H4,28,29,30)/t20-/m0/s1
InChIKey
OPNMQSFIGUSHDH-FQEVSTJZSA-N
PubChem Compound ID
5311374
PubChem Substance ID
7980404, 26755458, 39341055, 75162947, 114155932, 135650501, 242254519
Target and Pathway
Target(s) Somatostatin receptor type 4 Target Info Agonist [534729]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539318(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2082).
Ref 534729Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry. Science. 1998 Oct 23;282(5389):737-40.

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