Drug General Information
Drug ID	D0P3SU
Former ID	DNC013434
Drug Name	N-hydroxy-3-phenoxybenzamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528719]
Structure		Download 2D MOL 3D MOL
Formula	C13H11NO3
Canonical SMILES	C1=CC=C(C=C1)OC2=CC=CC(=C2)C(=O)NO
InChI	1S/C13H11NO3/c15-13(14-16)10-5-4-8-12(9-10)17-11-6-2-1-3-7-11/h1-9,16H,(H,14,15)
InChIKey	WFZFBIHVPMBSOS-UHFFFAOYSA-N
PubChem Compound ID	10192705
Target and Pathway
Target(s)	Histone Deacetylase 8	Target Info	Inhibitor	[528719]
KEGG Pathway	Alcoholism
	Viral carcinogenesis
PANTHER Pathway	Wnt signaling pathway
Pathway Interaction Database	Signaling events mediated by HDAC Class I
Reactome	NOTCH1 Intracellular Domain Regulates Transcription
	Constitutive Signaling by NOTCH1 PEST Domain Mutants
	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
	HDACs deacetylate histones
WikiPathways	Integrated Pancreatic Cancer Pathway
	Neural Crest Differentiation
	Cell Cycle
References
Ref 528719	Bioorg Med Chem Lett. 2007 May 15;17(10):2874-8. Epub 2007 Feb 25.Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors.
Ref 528719	Bioorg Med Chem Lett. 2007 May 15;17(10):2874-8. Epub 2007 Feb 25.Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors.

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