Drug Information

Drug General Information
Drug ID
D09VTY
Former ID
DIB019866
Drug Name
FMS586
Synonyms
FMS 586; FMS-586
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538949]
Structure
Download
2D MOL
Formula
C24H30N4O
InChI
InChI=1S/C24H30N4O/c1-17(2)28-22-7-5-4-6-20(22)21-16-19(8-9-23(21)28)26-24(29)27(3)15-12-18-10-13-25-14-11-18/h8-11,13-14,16-17H,4-7,12,15H2,1-3H3,(H,26,29)
InChIKey
YLNOMVNCZMWDST-UHFFFAOYSA-N
PubChem Compound ID
11589975
PubChem Substance ID
42756817, 53860483, 77036663, 135650281, 136352781, 247253499
Target and Pathway
Target(s) Neuropeptide Y receptor 5 Target Info Antagonist [527988]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 538949(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1563).
Ref 527988Pharmacological characterization and feeding-suppressive property of FMS586 [3-(5,6,7,8-tetrahydro-9-isopropyl-carbazol-3-yl)-1-methyl-1-(2-pyridin-4-yl-ethyl)-urea hydrochloride], a novel, selective, and orally active antagonist for neuropeptide Y Y5 receptor. J Pharmacol Exp Ther. 2006 May;317(2):562-70. Epub 2006 Jan 25.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.