Drug General Information
Drug ID
D06MBI
Former ID
DIB019089
Drug Name
TG003
Synonyms
Clk inhibitor; TG003; TG 003; TG-003
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541226]
Structure
Download
2D MOL

3D MOL

Formula
C13H15NO2S
InChI
InChI=1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3/b13-7-
InChIKey
BGVLELSCIHASRV-QPEQYQDCSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) CDC-like kinase 2 Target Info Inhibitor [529213]
Cdc2-like kinase 1 Target Info Inhibitor [529213]
NetPath Pathway TCR Signaling Pathway
EGFR1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
WikiPathways mRNA Processing
References
Ref 541226(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5942).
Ref 529213Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20523-8. Epub 2007 Dec 11.A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.