Drug Information

Drug General Information
Drug ID
D05CEM
Former ID
DIB020554
Drug Name
NNC269100
Synonyms
NNC-269100; NNC 269100
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540451]
Structure
Download
2D MOL
Formula
C22H25BrCl2N6O
InChI
InChI=1S/C22H25BrCl2N6O/c23-17-5-7-21(29-12-17)31(14-16-4-6-19(24)20(25)11-16)10-2-9-28-22(32)27-8-1-3-18-13-26-15-30-18/h4-7,11-13,15H,1-3,8-10,14H2,(H,26,30)(H2,27,28,32)
InChIKey
QJDXAQZNKZDALD-UHFFFAOYSA-N
PubChem Compound ID
5311371
PubChem Substance ID
7980401, 39341052, 50777134, 85209206, 89449196, 114155923, 178100498, 242276797
Target and Pathway
Target(s) Somatostatin receptor type 4 Target Info Agonist [534752]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 540451(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3513).
Ref 534752Nonpeptide somatostatin agonists with sst4 selectivity: synthesis and structure-activity relationships of thioureas. J Med Chem. 1998 Nov 19;41(24):4693-705.

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