Drug Information

Drug General Information
Drug ID
D08GSF
Former ID
DAP000995
Drug Name
Proflavine
Synonyms
PRL; Proflavin; Proflavina; Proflavinum; Profura; Progarmed; Isoflav base; Proflavine [INN]; Proflavine hemisulfate; Proflavina [INN-Spanish]; Proflavine Hemi-Sulfate; Proflavinum [INN-Latin]; Profoliol-B; AE-562/12222295; Acridine-3,6-diamine; 2,8-Diaminoacridine; 2,8-Diaminoacridine (European); 2,8-Diaminoacridinium; 3,6-ACRIDINEDIAMINE; 3,6-Acridinediamine hydrochloride; 3,6-Diamino-acridinium; 3,6-Diaminoacridine; 3,6-Diaminoacridine sulfate; 3,6-Diaminoacridinium; 3,7-Diamino-5-azaanthracene
Drug Type
Small molecular drug
Indication Sepsis [ICD9: 995.91; ICD10:A40, A41] Approved [550748]
Therapeutic Class
Antiinfective Agents
Structure
Download
2D MOL

3D MOL
Formula
C13H11N3
Canonical SMILES
C1=CC(=CC2=NC3=C(C=CC(=C3)N)C=C21)N
InChI
1S/C13H11N3/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10/h1-7H,14-15H2
InChIKey
WDVSHHCDHLJJJR-UHFFFAOYSA-N
CAS Number
CAS 92-62-6
PubChem Compound ID
7099
PubChem Substance ID
13362, 597206, 831294, 6902239, 7890047, 8154696, 10538028, 11409033, 11409157, 11436429, 11446857, 14773275, 16959146, 26703197, 29218003, 29226007, 46391536, 46393030, 46393031, 46505401, 46513046, 49864280, 51075611, 57323951, 57581409, 58017465, 79664590, 85088913, 85088914, 85256541, 87349924, 87691790, 96100151, 103244999, 104313972, 117528939, 117528940, 118081085, 121282165, 124360823, 124513852, 124893244, 125649137, 126678395, 126691684, 129567308, 131732471, 134338265, 134972357, 137005971
ChEBI ID
ChEBI:8452
Target and Pathway
Target(s) DNA Target Info Binder [537222]
References
Ref 550748Drug information of Proflavine, 2008. eduDrugs.
Ref 537222Interaction of small molecules with double-stranded RNA: spectroscopic, viscometric, and calorimetric study of hoechst and proflavine binding to PolyCG structures. DNA Cell Biol. 2009 Apr;28(4):209-19.

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