Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03WJG
|
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| Former ID |
DIB019302
|
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| Drug Name |
compound 1a
|
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| Drug Type |
Small molecular drug
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C18H20N2O8S
|
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| InChI |
InChI=1S/C18H20N2O8S/c21-14-10-20(15(18(24)19-25)17(23)16(14)22)29(26,27)13-8-6-12(7-9-13)28-11-4-2-1-3-5-11/h1-9,14-17,21-23,25H,10H2,(H,19,24)/t14-,15+,16+,17+/m0/s1
|
||||
| InChIKey |
WLWNRAWQDZRXMB-YLFCFFPRSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | MMP-9 | Target Info | Inhibitor | [527019] | |
| Pathway Interaction Database | LPA receptor mediated events | ||||
| Plasma membrane estrogen receptor signaling | |||||
| Osteopontin-mediated events | |||||
| Validated transcriptional targets of AP1 family members Fra1 and Fra2 | |||||
| Validated targets of C-MYC transcriptional activation | |||||
| CXCR4-mediated signaling events | |||||
| amb2 Integrin signaling | |||||
| Syndecan-4-mediated signaling events | |||||
| AP-1 transcription factor network | |||||
| Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||||
| Syndecan-1-mediated signaling events | |||||
| Regulation of nuclear beta catenin signaling and target gene transcription | |||||
| FGF signaling pathway | |||||
| WikiPathways | Endochondral Ossification | ||||
| IL1 and megakaryotyces in obesity | |||||
| Mammary gland development pathway - Involution (Stage 4 of 4) | |||||
| Activation of Matrix Metalloproteinases | |||||
| Degradation of collagen | |||||
| Spinal Cord Injury | |||||
| AGE/RAGE pathway | |||||
| TWEAK Signaling Pathway | |||||
| Angiogenesis | |||||
| Osteopontin Signaling | |||||
| Matrix Metalloproteinases | |||||
| References | |||||
| Ref 527019 | Azasugar-based MMP/ADAM inhibitors as antipsoriatic agents. J Med Chem. 2004 Apr 8;47(8):1930-8. | ||||
| Ref 541651 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6514). | ||||
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