Drug Information

Drug General Information
Drug ID
D03WPA
Former ID
DAP000652
Drug Name
Trovafloxacin
Synonyms
TVFX; Trovan; Fluorinated quinolone; Trovafloxacin [INN]; CP 99219; CP99219; CP 99,219; CP-99219;Trovafloxacin (INN); Trovan (TN); Trovan (oral); Turvel (TN); CP-99,219; (1alpha,5alpha,6alpha)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; 7-((1R,5S)-6-Amino-3-aza-bicyclo[3.1.0]hex-3-yl)-1-(2,4-difluoro-phenyl)-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid; 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid; 7-[(1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; 7-[(1r,5s)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [538605]
Therapeutic Class
Antiinfective Agents
Company
Pfizer Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C20H15F3N4O3
Canonical SMILES
C1C2C(C2N)CN1C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)<br />F)C(=O)O)F
InChI
1S/C20H15F3N4O3/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24/h1-4,7,10-11,16H,5-6,24H2,(H,29,30)/t10-,11+,16?
InChIKey
WVPSKSLAZQPAKQ-SOSAQKQKSA-N
CAS Number
CAS 147059-72-1
PubChem Compound ID
62959
PubChem Substance ID
9866, 604763, 644006, 14831391, 17187237, 32961437, 43120003, 46508751, 49996898, 50940561, 56312374, 56314400, 57288868, 57314924, 96025337, 96099865, 104234146, 104327073, 104826295, 117509495, 124766049, 126666094, 129640810, 134337942, 135021037, 135029115, 135367547, 137003457, 143130985, 152049315, 160964030, 162793562, 175265560, 179316262, 179678466, 184527292, 223403934, 223403935, 223441011, 223659710, 225068555, 226420920, 226420921, 234609108, 252216525, 252358281
SuperDrug ATC ID
J01MA13
SuperDrug CAS ID
cas=147059721
Target and Pathway
Target(s) Bacterial DNA gyrase Target Info Modulator [556264]
References
Ref 538605FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 050762.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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