TTD | Drug: D0I1AF

Drug General Information
Drug ID	D0I1AF
Former ID	DNC007967
Drug Name	7-vinyl-6H-chromeno[4,3-b]quinoline-3,9-diol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528822]
Structure		Download 2D MOL 3D MOL
Formula	C18H13NO3
Canonical SMILES	C=CC1=C2COC3=CC(=O)C=CC3=C2NC4=C1C=C(C=C4)O
InChI	1S/C18H13NO3/c1-2-12-14-7-10(20)4-6-16(14)19-18-13-5-3-11(21)8-17(13)22-9-15(12)18/h2-8,19-20H,1,9H2
InChIKey	IQTGZSIQDWJUBU-UHFFFAOYSA-N
PubChem Compound ID	11572869
Target and Pathway
Target(s)	Steroid hormone receptor ERR1	Target Info	Inhibitor	[528822]
Reactome	PPARA activates gene expression
	Transcriptional activation of mitochondrial biogenesis
	Nuclear Receptor transcription pathway
WikiPathways	Mitochondrial Gene Expression
	Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
	Nuclear Receptors
References
Ref 528822	Bioorg Med Chem Lett. 2007 Jul 15;17(14):4053-6. Epub 2007 May 4.ERbeta ligands. Part 6: 6H-Chromeno[4,3-b]quinolines as a new series of estrogen receptor beta-selective ligands.
Ref 528822	Bioorg Med Chem Lett. 2007 Jul 15;17(14):4053-6. Epub 2007 May 4.ERbeta ligands. Part 6: 6H-Chromeno[4,3-b]quinolines as a new series of estrogen receptor beta-selective ligands.

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Drug Information