Drug Information

Drug General Information
Drug ID
D0M6TB
Former ID
DIB020525
Drug Name
NF157
Synonyms
NF-157
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539111]
Structure
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2D MOL
Formula
C49H34F2N6O23S6
InChI
InChI=1S/C49H34F2N6O23S6/c50-33-9-7-25(47(60)54-35-11-13-39(83(69,70)71)31-19-29(81(63,64)65)21-41(43(31)35)85(75,76)77)17-37(33)56-45(58)23-3-1-5-27(15-23)52-49(62)53-28-6-2-4-24(16-28)46(59)57-38-18-26(8-10-34(38)51)48(61)55-36-12-14-40(84(72,73)74)32-20-30(82(66,67)68)22-42(44(32)36)86(78,79)80/h1-22H,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)
InChIKey
UDVIAMRWOLIUAE-UHFFFAOYSA-N
PubChem Compound ID
11636757
PubChem Substance ID
77885343, 135650710, 229384019, 242113920, 248537584
Target and Pathway
Target(s) P2Y11 receptor Target Info Antagonist [527825]
References
Ref 539111(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1761).
Ref 527825J Med Chem. 2005 Nov 3;48(22):7040-8.Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency.

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