Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00GOS
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| Former ID |
DAP001190
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| Drug Name |
Clocortolone
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| Synonyms |
Clocortolona; Clocortolonum; Clocortolone (INN); (6S,8S,9R,10S,11S,13S,14S,16R,17S)-9-chloro-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one; 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methyl-1,4-pregnadien-3,20-dione; 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione; 9-chloro-6alpha-fluoro-16alpha-methyl-1,4-pregnadiene-11beta,21-diol-3,20-dione
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| Drug Type |
Small molecular drug
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| Indication | Inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp [ICD10:L20-L30] | Approved | [551871] | ||
| Company |
Promius Pharma Llc
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| Structure |
|
Download2D MOL |
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| Formula |
C22H28ClFO4
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| Canonical SMILES |
CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1C(=O)CO)C)O)Cl)C)F
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| InChI |
1S/C22H28ClFO4/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-21(15,3)22(14,23)18(28)9-20(13,2)19(11)17(27)10-25/h4-5,7,11,13-14,16,18-19,25,28H,6,8-10H2,1-3H3/t11-,13+,14+,16+,18+,19-,20+,21+,22+/m1/s1
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| InChIKey |
YMTMADLUXIRMGX-RFPWEZLHSA-N
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| CAS Number |
CAS 34097-16-0
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| SuperDrug ATC ID |
D07AB21
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| SuperDrug CAS ID |
cas=004828277
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| Target and Pathway | |||||
| Target(s) | Phospholipase A2 | Target Info | Inducer | [537815] | |
| BioCyc Pathway | Phospholipases | ||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
| WikiPathways | Glycerophospholipid biosynthesis | ||||
| References | |||||
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