Drug Information

Drug General Information
Drug ID
D03LLM
Former ID
DIB020959
Drug Name
SLG
Synonyms
1-stearoyl-2-linoleoyl-sn-glycerol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539570]
Structure
Download
2D MOL
Formula
C39H72O5
InChI
InChI=1S/C39H72O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h12,14,18,20,37,40H,3-11,13,15-17,19,21-36H2,1-2H3/b14-12-,20-18-/t37-/m0/s1
InChIKey
AJMZUFBKADIAKC-SKTOPKGQSA-N
PubChem Compound ID
6441562
PubChem Substance ID
11968798, 14710902, 26756763, 26756764, 43034217, 47216539, 47216540, 47515078, 50111409, 57369211, 80097550, 92309821, 99300735, 99302253, 114563684, 126526163, 135126709, 135651560, 172121058, 179205549, 228049189, 242451859, 250133129, 252455545
Target and Pathway
Target(s) Short transient receptor potential channel 6 Target Info Activator [534828]
PANTHER Pathway Alzheimer disease-presenilin pathway
Pathway Interaction Database Endothelins
Nephrin/Neph1 signaling in the kidney podocyte
EPO signaling pathway
PAR1-mediated thrombin signaling events
Reactome Effects of PIP2 hydrolysis
TRP channels
Role of second messengers in netrin-1 signaling
WikiPathways Primary Focal Segmental Glomerulosclerosis FSGS
Platelet homeostasis
Netrin-1 signaling
GPCR downstream signaling
Effects of PIP2 hydrolysis
References
Ref 539570(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2442).
Ref 534828Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature. 1999 Jan 21;397(6716):259-63.

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