Drug Information

Drug General Information
Drug ID
D00QIA
Former ID
DNC006244
Drug Name
(S)-tert-butyl 4-methyl-1-oxopentan-2-ylcarbamate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527872]
Structure
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2D MOL

3D MOL
Formula
C11H21NO3
Canonical SMILES
CC(C)CC(C=O)NC(=O)OC(C)(C)C
InChI
1S/C11H21NO3/c1-8(2)6-9(7-13)12-10(14)15-11(3,4)5/h7-9H,6H2,1-5H3,(H,12,14)/t9-/m0/s1/i7+1
InChIKey
RQSBRFZHUKLKNO-WQVCYBKOSA-N
PubChem Compound ID
104275
Target and Pathway
Target(s) Cathepsin K Target Info Inhibitor [527872]
KEGG Pathway Lysosome
Osteoclast differentiation
Toll-like receptor signaling pathway
Rheumatoid arthritis
NetPath Pathway TGF_beta_Receptor Signaling Pathway
RANKL Signaling Pathway
IL2 Signaling Pathway
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Trafficking and processing of endosomal TLR
MHC class II antigen presentation
WikiPathways RANKL/RANK Signaling Pathway
Osteoclast Signaling
References
Ref 527872Bioorg Med Chem Lett. 2006 Feb 15;16(4):978-83. Epub 2005 Nov 15.Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?.
Ref 527872Bioorg Med Chem Lett. 2006 Feb 15;16(4):978-83. Epub 2005 Nov 15.Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?.

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