TTD | Drug: D0V3DQ

Drug General Information
Drug ID	D0V3DQ
Former ID	DIB018326
Drug Name	[3H]LXA4
Synonyms	[3H]-LXA4
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540356]
Formula	C20H32O5
InChI	InChI=1S/C20H34O5/c1-2-3-8-12-17(21)13-9-6-4-5-7-10-14-18(22)19(23)15-11-16-20(24)25/h5,7,9-10,13-14,17-19,21-23H,2-4,6,8,11-12,15-16H2,1H3,(H,24,25)/b7-5+,13-9+,14-10+/t17-,18+,19-/m0/s1/i4T,6T
InChIKey	BIAXEQCLMUBCBP-BASHJZMHSA-N
PubChem Compound ID	5280914
Target and Pathway
Target(s)	FMLP-related receptor I	Target Info	Agonist	[526742]
Pathway Interaction Database	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome	G alpha (q) signalling events
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 540356	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3411).
Ref 526742	Lipoxin recognition sites. Specific binding of labeled lipoxin A4 with human neutrophils. J Biol Chem. 1992 Aug 15;267(23):16168-76.

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Drug Information