Drug General Information
Drug ID
D09UVB
Former ID
DIB020017
Drug Name
HTMT
Synonyms
histamine-trifluoromethyl-toluidine; histamine-trifluoromethyltoluide; HTFMT
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538787]
Structure
Download
2D MOL
Formula
C19H25F3N4O
InChI
InChI=1S/C19H25F3N4O/c1-14(24-11-10-17-12-23-13-25-17)4-2-3-5-18(27)26-16-8-6-15(7-9-16)19(20,21)22/h6-9,12-14,24H,2-5,10-11H2,1H3,(H,23,25)(H,26,27)
InChIKey
PMKJGGBYYNEYPA-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Histamine H4 receptor Target Info Agonist [525965]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 538787(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1273).
Ref 525965Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol Pharmacol. 2001 Mar;59(3):434-41.

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