TTD | Drug: D0D5NP

Drug General Information
Drug ID	D0D5NP
Former ID	DIB020430
Drug Name	MRS2496
Synonyms	MRS-2496
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539075]
Structure		Download 2D MOL
Formula	C10H16ClN5O6P2
InChI	InChI=1S/C10H16ClN5O6P2/c1-12-8-7-9(15-10(11)14-8)16(5-13-7)2-6(3-23(17,18)19)4-24(20,21)22/h5-6H,2-4H2,1H3,(H,12,14,15)(H2,17,18,19)(H2,20,21,22)
InChIKey	FFBIISIICFTESN-UHFFFAOYSA-N
PubChem Compound ID	10894633
PubChem Substance ID	15942110, 23140124, 42074752, 74805916, 103401007, 104014725, 135650658
Target and Pathway
Target(s)	P2Y purinoceptor 1	Target Info	Antagonist	[527243]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	Platelet activation
Reactome	G alpha (q) signalling events
	P2Y receptors
	ADP signalling through P2Y purinoceptor 1
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539075	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1723).
Ref 527243	Antiaggregatory activity in human platelets of potent antagonists of the P2Y 1 receptor. Biochem Pharmacol. 2004 Nov 15;68(10):1995-2002.

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Drug Information