Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05YJR
|
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| Former ID |
DNC009265
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| Drug Name |
GARCINONE D
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [531095] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C24H28O7
|
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| Canonical SMILES |
CC(=CCC1=C(C=C2C(=C1O)C(=O)C3=C(C(=C(C=C3O2)O)OC)CCC(C)<br />(C)O)O)C
|
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| InChI |
1S/C24H28O7/c1-12(2)6-7-13-15(25)10-18-20(21(13)27)22(28)19-14(8-9-24(3,4)29)23(30-5)16(26)11-17(19)31-18/h6,10-11,25-27,29H,7-9H2,1-5H3
|
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| InChIKey |
TYALNCRUIKOKGP-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Neuraminidase | Target Info | Inhibitor | [531095] | |
| Cytochrome P450 19 | Target Info | Inhibitor | [529538] | ||
| NetPath Pathway | FSH Signaling Pathway | ||||
| PANTHER Pathway | Androgen/estrogene/progesterone biosynthesis | ||||
| PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
| Reactome | Endogenous sterols | ||||
| References | |||||
| Ref 529538 | J Nat Prod. 2008 Jul;71(7):1161-6. Epub 2008 Jun 18.Xanthones from the botanical dietary supplement mangosteen (Garcinia mangostana) with aromatase inhibitory activity. | ||||
| Ref 531095 | Bioorg Med Chem. 2010 Sep 1;18(17):6258-64. Epub 2010 Jul 19.Xanthones with neuraminidase inhibitory activity from the seedcases of Garcinia mangostana. | ||||
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