Drug Information

Drug General Information
Drug ID
D05JMJ
Former ID
DIB018997
Drug Name
BN-81,674
Synonyms
BN 81,674; BN81,674; BN-81674; BN81674; BN 81674
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539313]
Structure
Download
2D MOL
Formula
C30H38N4
InChI
InChI=1S/C30H38N4/c1-3-5-12-18-30(19-13-6-4-2)28-24(23-16-10-11-17-25(23)32-28)20-26(34-30)29-31-21-27(33-29)22-14-8-7-9-15-22/h7-11,14-17,21,26,32,34H,3-6,12-13,18-20H2,1-2H3,(H,31,33)/t26-/m1/s1
InChIKey
DGSMSHNIDMODOQ-AREMUKBSSA-N
PubChem Compound ID
5311378
PubChem Substance ID
7980410, 14882213, 39341059, 57359456, 77023547, 114155944, 135650012, 140418961, 172649825, 198955526, 237925069, 245571364
Target and Pathway
Target(s) Somatostatin receptor type 3 Target Info Agonist [526127]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539313(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2071).
Ref 526127Identification of potent non-peptide somatostatin antagonists with sst(3) selectivity. J Med Chem. 2001 Aug 30;44(18):2990-3000.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.