TTD | Drug: D0L1RZ

Drug General Information
Drug ID	D0L1RZ
Former ID	DNC009390
Drug Name	3-(4-methoxyphenyl)quinoxaline-5-carboxamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529901]
Structure		Download 2D MOL 3D MOL
Formula	C16H13N3O2
Canonical SMILES	COC1=CC=C(C=C1)C2=NC3=C(C=CC=C3N=C2)C(=O)N
InChI	1S/C16H13N3O2/c1-21-11-7-5-10(6-8-11)14-9-18-13-4-2-3-12(16(17)20)15(13)19-14/h2-9H,1H3,(H2,17,20)
InChIKey	XLKSSLKAULIQEE-UHFFFAOYSA-N
PubChem Compound ID	9965481
Target and Pathway
Target(s)	Poly [ADP-ribose] polymerase-1	Target Info	Inhibitor	[529901]
KEGG Pathway	Base excision repair
KEGG Pathway	NF-kappa B signaling pathway
PANTHER Pathway	FAS signaling pathway
Pathway Interaction Database	Integrin-linked kinase signaling
	Caspase Cascade in Apoptosis
	Notch-mediated HES/HEY network
Reactome	Dual Incision in GG-NER
WikiPathways	FAS pathway and Stress induction of HSP regulation
	Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
	Nanoparticle triggered regulated necrosis
	Corticotropin-releasing hormone
References
Ref 529901	J Med Chem. 2009 Feb 12;52(3):718-25.Design, synthesis, and cytoprotective effect of 2-aminothiazole analogues as potent poly(ADP-ribose) polymerase-1 inhibitors.
Ref 529901	J Med Chem. 2009 Feb 12;52(3):718-25.Design, synthesis, and cytoprotective effect of 2-aminothiazole analogues as potent poly(ADP-ribose) polymerase-1 inhibitors.

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Drug Information