Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05MFG
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| Former ID |
DAP000911
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| Drug Name |
Spirapril
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| Synonyms |
Renormax; Sandopril; Setrilan; Espirapril [Spanish]; Not established; Spiraprilum [Latin]; Sch-33844; Spirapril (INN); Spirapril [INN:BAN]; TI-211-950; (2S)-3-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,9-dithia-3-azaspiro[4.4]nonane-2-carboxylic acid
|
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Antihypertensive Agents
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| Structure |
|
Download2D MOL |
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| Formula |
C22H30N2O5S2
|
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| InChI |
InChI=1S/C22H30N2O5S2/c1-3-29-21(28)17(10-9-16-7-5-4-6-8-16)23-15(2)19(25)24-14-22(30-11-12-31-22)13-18(24)20(26)27/h4-8,15,17-18,23H,3,9-14H2,1-2H3,(H,26,27)/t15-,17-,18-/m0/s1
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| InChIKey |
HRWCVUIFMSZDJS-SZMVWBNQSA-N
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| CAS Number |
CAS 83647-97-6
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7980648, 11056512, 12013873, 14858420, 39341121, 46506126, 49964144, 57359484, 79446638, 96025214, 103165488, 103928452, 114156121, 128104191, 134223240, 134338188, 135049040, 137003827, 141328414, 160964639, 163693574, 163852855, 178103189, 179151271, 198942493, 223621315, 224854639, 226407318, 252356740
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| SuperDrug ATC ID |
C09AA11
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| SuperDrug CAS ID |
cas=083647976
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| Target and Pathway | |||||
| Target(s) | Angiotensin-converting enzyme | Target Info | Inhibitor | [536133] | |
| PathWhiz Pathway | Angiotensin Metabolism | ||||
| References | |||||
| Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
| Ref 541698 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6575). | ||||
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