Drug Information

Drug General Information
Drug ID
D0L8DV
Former ID
DIB020924
Drug Name
SC46275
Synonyms
SC-46275
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540290]
Structure
Download
2D MOL
Formula
C25H36O5
InChI
InChI=1S/C25H36O5/c1-25(29,17-15-19-10-7-8-11-19)16-9-13-21-20(22(26)18-23(21)27)12-5-3-4-6-14-24(28)30-2/h3-4,9-10,13,15,17,20-21,23,27,29H,5-8,11-12,14,16,18H2,1-2H3/b4-3-,13-9+,17-15+/t20-,21-,23-,25-/m1/s1
InChIKey
ZZVPHCPLTZTOBC-ZNJGPPGCSA-N
PubChem Compound ID
5311427
PubChem Substance ID
7980577, 11056498, 14758004, 39341103, 51531441, 103233903, 114156067, 178100362, 198990615
Target and Pathway
Target(s) Prostaglandin E2 receptor EP3 subtype Target Info Agonist [528220]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Regulation of lipolysis in adipocytes
Pathways in cancer
NetPath Pathway IL2 Signaling Pathway
Reactome Prostanoid ligand receptors
G alpha (i) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 540290(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3331).
Ref 528220Investigation of the pronounced synergism between prostaglandin E2 and other constrictor agents on rat femoral artery. Prostaglandins Leukot Essent Fatty Acids. 2006 Jun;74(6):401-15.

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