Drug General Information
Drug ID
D0O7CX
Former ID
DNC014327
Drug Name
4'-Amino-4-hydroxychalcone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530713]
Structure
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2D MOL

3D MOL

Formula
C15H13NO2
Canonical SMILES
C1=CC(=CC=C1C=CC(=O)C2=CC=C(C=C2)N)O
InChI
1S/C15H13NO2/c16-13-6-4-12(5-7-13)15(18)10-3-11-1-8-14(17)9-2-11/h1-10,17H,16H2/b10-3+
InChIKey
GJKSOGFGWQZGRL-XCVCLJGOSA-N
PubChem Compound ID
Target and Pathway
Target(s) Tyrosine oxidase Target Info Inhibitor [530713]
BioCyc Pathway (S)-reticuline biosynthesis
Eumelanin biosynthesis
L-dopachrome biosynthesis
KEGG Pathway Tyrosine metabolism
Riboflavin metabolism
Metabolic pathways
Melanogenesis
PathWhiz Pathway Riboflavin Metabolism
Tyrosine Metabolism
WikiPathways Dopamine metabolism
References
Ref 530713Eur J Med Chem. 2010 May;45(5):2010-7. Epub 2010 Jan 28.Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone.
Ref 530713Eur J Med Chem. 2010 May;45(5):2010-7. Epub 2010 Jan 28.Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone.

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