Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05LXA
|
||||
| Former ID |
DNC008638
|
||||
| Drug Name |
1-(1-Biphenyl-4-yl-2-methyl-propyl)-1H-imidazole
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [529625] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C19H20N2
|
||||
| Canonical SMILES |
CC(C)C(C1=CC=C(C=C1)C2=CC=CC=C2)N3C=CN=C3
|
||||
| InChI |
1S/C19H20N2/c1-15(2)19(21-13-12-20-14-21)18-10-8-17(9-11-18)16-6-4-3-5-7-16/h3-15,19H,1-2H3
|
||||
| InChIKey |
IYAQGZVBLONFOB-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 17 alpha-hydroxylase-C17, 20-lyase | Target Info | Inhibitor | [529625] | |
| PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
| Steroidogenesis | |||||
| References | |||||
| Ref 529625 | Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. Epub 2008 Jul 9.Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge. | ||||
| Ref 529625 | Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. Epub 2008 Jul 9.Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.