Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01HUO
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| Former ID |
DNC007574
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| Drug Name |
BIS-IMIDE A
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [528838] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C16H7N3O4
|
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| Canonical SMILES |
C1=CC=C2C(=C1)C3=C4C(=C5C(=C3N2)C(=O)NC5=O)C(=O)NC4=O
|
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| InChI |
1S/C16H7N3O4/c20-13-8-7-5-3-1-2-4-6(5)17-12(7)11-10(9(8)14(21)18-13)15(22)19-16(11)23/h1-4,17H,(H,18,20,21)(H,19,22,23)
|
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| InChIKey |
IZHSJTMCSHXFHX-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Serine/threonine-protein kinase Chk1 | Target Info | Inhibitor | [528838] | |
| Pathway Interaction Database | Fanconi anemia pathway | ||||
| p73 transcription factor network | |||||
| ATR signaling pathway | |||||
| Circadian rhythm pathway | |||||
| p53 pathway | |||||
| Reactome | Activation of ATR in response to replication stress | ||||
| Processing of DNA double-strand break ends | |||||
| Presynaptic phase of homologous DNA pairing and strand exchange | |||||
| G2/M DNA damage checkpoint | |||||
| Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | |||||
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | |||||
| References | |||||
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