Drug Information

Drug General Information
Drug ID
D0Q9ZN
Former ID
DNC007929
Drug Name
3-(4-(benzyloxy)-3,5-dibromophenyl)propanoic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528640]
Structure
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2D MOL

3D MOL
Formula
C16H14Br2O3
Canonical SMILES
C1=CC=C(C=C1)COC2=C(C=C(C=C2Br)CCC(=O)O)Br
InChI
1S/C16H14Br2O3/c17-13-8-12(6-7-15(19)20)9-14(18)16(13)21-10-11-4-2-1-3-5-11/h1-5,8-9H,6-7,10H2,(H,19,20)
InChIKey
ZCVQDNGOBFARHQ-UHFFFAOYSA-N
PubChem Compound ID
23648092
Target and Pathway
Target(s) Thyroid hormone receptor alpha Target Info Inhibitor [528640]
Thyroid hormone receptor beta-1 Target Info Inhibitor [528640]
KEGG Pathway Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathwayhsa04080:Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathway
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptorrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptor
Reactome Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
WikiPathways Endochondral Ossification
Nuclear ReceptorsWP706:SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Nuclear Receptors
References
Ref 528640Bioorg Med Chem Lett. 2007 Apr 1;17(7):2018-21. Epub 2007 Jan 13.Thyroid receptor ligands. Part 7: Indirect antagonists of the thyroid hormone receptor with improved affinity.
Ref 528640Bioorg Med Chem Lett. 2007 Apr 1;17(7):2018-21. Epub 2007 Jan 13.Thyroid receptor ligands. Part 7: Indirect antagonists of the thyroid hormone receptor with improved affinity.

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