Drug Information

Drug General Information
Drug ID
D03LVI
Former ID
DNC010860
Drug Name
AMG-2504
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551343]
Structure
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2D MOL

3D MOL
Formula
C15H10Cl4N2O3S
Canonical SMILES
C1=CC(=CC=C1C(=O)NC(C(Cl)(Cl)Cl)SC2=CC=C(C=C2)Cl)[N+](=<br />O)[O-]
InChI
1S/C15H10Cl4N2O3S/c16-10-3-7-12(8-4-10)25-14(15(17,18)19)20-13(22)9-1-5-11(6-2-9)21(23)24/h1-8,14H,(H,20,22)
InChIKey
DNTIPHKVCXUYRM-UHFFFAOYSA-N
PubChem Compound ID
2830271
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Inhibitor [551343]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 551343Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. J Med Chem. 2010 Jul 22;53(14):5085-107. doi: 10.1021/jm100062h.
Ref 551343Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. J Med Chem. 2010 Jul 22;53(14):5085-107. doi: 10.1021/jm100062h.

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