Drug General Information
Drug ID
D0O8PM
Former ID
DNC007637
Drug Name
N,N-bis(cyanomethyl)-3,4-dimethoxybenzamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529037]
Structure
Download
2D MOL

3D MOL

Formula
C13H13N3O3
Canonical SMILES
COC1=C(C=C(C=C1)C(=O)N(CC#N)CC#N)OC
InChI
1S/C13H13N3O3/c1-18-11-4-3-10(9-12(11)19-2)13(17)16(7-5-14)8-6-15/h3-4,9H,7-8H2,1-2H3
InChIKey
GZUJYYKDHAQDKU-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Leukocyte elastase Target Info Inhibitor [529037]
KEGG Pathway Transcriptional misregulation in cancer
Systemic lupus erythematosus
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
C-MYB transcription factor network
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
WikiPathways Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Human Complement System
Degradation of collagen
References
Ref 529037J Med Chem. 2007 Oct 4;50(20):4928-38. Epub 2007 Sep 12.N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase.
Ref 529037J Med Chem. 2007 Oct 4;50(20):4928-38. Epub 2007 Sep 12.N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase.

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