Drug Information

Drug General Information
Drug ID
D07LNY
Former ID
DIB020762
Drug Name
prostaglandin A2
Synonyms
medullin; PGA2
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541431]
Structure
Download
2D MOL
Formula
C20H30O4
InChI
InChI=1S/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12-18,21H,2-3,5-6,8-11H2,1H3,(H,23,24)/b7-4-,14-12+/t16-,17-,18+/m0/s1
InChIKey
MYHXHCUNDDAEOZ-FOSBLDSVSA-N
PubChem Compound ID
5280880
PubChem Substance ID
8237, 599108, 855670, 4265975, 8616420, 14717647, 14924515, 24898548, 26522686, 26751479, 26751480, 39289869, 47216545, 47216546, 50026811, 50103989, 53788336, 57357905, 79622497, 85787701, 92298423, 92309876, 99300790, 99302308, 103756910, 104046431, 113854152, 135056758, 137007967, 139340658, 162225876, 164814196, 178102899, 179205555, 198943825, 228253856, 250136889, 252356257, 252455600, 252457317, 252469022
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Activator [529635]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 541431(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6279).
Ref 529635Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12045-50.

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